See What Is New In Dementia Research

Periodically I will search the web for newly publicized results of trials and will post them here. So far, no “magic bullets” have been discovered and many scientists are focusing on present healthy populations to see what lifestyle differences may benefit/protect the participants as they age.
It’s a multi-year study so we won’t be hearing what they have learned for a while!

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Biochemical Trigger Found May Be What Causes Alzheimer’s Disease

Scientists at the Instituto de Neurociencias de Alicante (Spain) reported some new findings in Alzheimer’s Research & Therapy. In Alzheimer’s Disease there are build-ups of two types of proteins in the brain: amyloid plaques and tau protein tangles. Beta-amyloid is a fragment of the larger protein called amyloid precursor protein (APP). When APP is broken down it either forms harmless proteins or the beta-amyloid during a process called glycosylation. The senior author, Javier Saez-Valero said this is dependent upon what sugar form is attached in the glycosylation process.

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The APOE4 Gene Disrupts Endocytosis, But The PICALM Gene Can Negate That Defect

Astrocytes help communication between neurons by maintaining the homeostasis for those cells. Those astrocytes that possess the APOE4 gene have impaired communication and are unable to maintain the metabolic needs of the cells they are supposed to help.

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New Blood Test On The Horizon

The most recent Alzheimer’s Association International Conference July 28-31, 2020 released news of a blood test that detects abnormal forms of tau protein (one of which is p-tau 217) one of the hallmarks of Alzheimer’s Disease (AD) besides the amyloid plaques that accumulate in the brain. To date the only way to pick up tau levels was by testing spinal fluid or looking at a PET scan of the brain for amyloid plaque damage. This plasma test correlates well with the increase of amyloid in the brain as well, but detects it’s presence years before the damage to the brain shows outward signs.

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Tips For Caregivers Of The Newly Diagnosed

I have listed numerous tips that might help you in your quest to have a more successful caregiver experience. As with everything else you have to judge where your loved-one is in the disease process, and whether what you are reading would work for him/her. Some may be past the point where a particular tip will help, so if it doesn’t, so be it. This is a time in your life where every day you have to learn to be flexible! If you can, then your caregiving experience will be much more successful and have less of a negative impact on you.

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Steps To Take After A Dementia Diagnosis

There are a number of steps to take once the dementia is confirmed by a neurologist. The steps don’t have to be done exactly in this order, but if you address them you will be in much better shape to follow your dementia journey.

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My Way Of Feeling In Control During COVID-19

Once New York was given the order to shut down schools, restaurants, and non-essential industries I saw a way I could help. It made my heart beat faster when I heard I could make cloth masks for hospitals in our area. I couldn’t move fast enough. This was a way I could cope and contribute even though I was a retired microbiologist and 71 years of age.

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Caregiving During The COVID-19 Virus Restrictions

Caregiving during the COVID-19 virus restrictions can add additional stress and isolation to your already burdened lifestyle. Now more than ever, it is important for the caregiver to maintain your “lifelines” of socialization with friends and family. Take this moment in time to learn new ways of keeping in touch to keep yourself rooted in your community!

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